Anti-ENT1 antibody (410-460) {FITC}

Clonality:	Polyclonal
Conjugation:	FITC
Isotype:	IgG
Purification:	Affinity Purified
Concentration:	0.5 µg/µl
Dilution Range:	WB: 1:500 ELISA: 1:10, 000 IP: 1:200 IHC: 1:100
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	Slc29a1
Gene ID:	63959
Uniprot ID:	S29A1_MOUSE
Immunogen Region:	410-460
Immunogen:	Synthetic peptide taken within amino acid reigon 410-460 on mouse Equilibrative nitrobenzylthioinosine-sensitive nucleoside transporter ENT1 protein.

Tissue Specificity	Highly expressed in heart, spleen, lung, liver and testis. Lower level of expression in brain and kidney. Expressed in adipose tissues, brown adipocytes expressing significantly higher amounts than white adipocytes. Expressed in seminiferous tubules.
Post Translational Modifications	Glycosylated.
Function	Uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis. Functions as a Na(+)-independent transporter. Involved in the transport of nucleosides such as adenosine, guanosine, inosine, uridine, thymidine and cytidine. Also transports purine (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil). Mediates basolateral nucleoside uptake into Sertoli cells, thereby regulating the transport of nucleosides in testis across the blood-testis-barrier. Regulates inosine levels in brown adipocytes tissues (BAT) and extracellular inosine levels, which controls BAT-dependent energy expenditure.
Protein Name	Equilibrative Nucleoside Transporter 1 Ment1 Equilibrative Nitrobenzylmercaptopurine Riboside-Sensitive Nucleoside Transporter Equilibrative Nbmpr-Sensitive Nucleoside Transporter Nucleoside Transporter - Es-Type Solute Carrier Family 29 Member 1
Database Links	Reactome: R-MMU-83936 Reactome: -MMU-9748787 Reactome: -MMU-9755088
Cellular Localisation	Basolateral Cell Membrane Multi-Pass Membrane Protein Apical Cell Membrane Cell Membrane
Alternative Antibody Names	Anti-Equilibrative Nucleoside Transporter 1 antibody Anti-Ment1 antibody Anti-Equilibrative Nitrobenzylmercaptopurine Riboside-Sensitive Nucleoside Transporter antibody Anti-Equilibrative Nbmpr-Sensitive Nucleoside Transporter antibody Anti-Nucleoside Transporter - Es-Type antibody Anti-Solute Carrier Family 29 Member 1 antibody Anti-Slc29a1 antibody Anti-Ent1 antibody

Information sourced from Uniprot.org

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