General Info
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-FDPS (120-419) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:100-1:500 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
| Gene Symbol: | FDPS |
| Gene ID: | 2224 |
| Uniprot ID: | FPPS_HUMAN |
| Immunogen Region: | 120-419 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-419 of human FPS/FDPS (NP_001995.1). |
| Immunogen Sequence: | IGGKYNRGLTVVVAFRELVE PRKQDADSLQRAWTVGWCVE LLQAFFLVADDIMDSSLTRR GQICWYQKPGVGLDAINDAN LLEACIYRLLKLYCREQPYY LNLIELFLQSSYQTEIGQTL DLLTAPQGNVDLVRFTEKRY KSIVKYKTAFYSFYLPIAAA MYMAGIDGEKEHANAKKILL EMGEFFQIQDDYLDLFGDPS VTGKIGTDIQDNKCSWLVVQ CLQRATPEQYQILKENYGQ |
Description
| Function | Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate. |
| Protein Name | Farnesyl Pyrophosphate SynthaseFpp SynthaseFps(2e -6e-Farnesyl Diphosphate SynthaseDimethylallyltranstransferaseFarnesyl Diphosphate SynthaseGeranyltranstransferase |
| Database Links | Reactome: R-HSA-191273Reactome: R-HSA-2426168 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Farnesyl Pyrophosphate Synthase antibodyAnti-Fpp Synthase antibodyAnti-Fps antibodyAnti-(2e -6e-Farnesyl Diphosphate Synthase antibodyAnti-Dimethylallyltranstransferase antibodyAnti-Farnesyl Diphosphate Synthase antibodyAnti-Geranyltranstransferase antibodyAnti-FDPS antibodyAnti-FPS antibodyAnti-KIAA1293 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance