Reagenti e strumenti per immunologia, biologia cellulare e biologia molecolare

Anti-Kir2.2 K+ Channel Antibody FL550 Conjugate

Stampa

Cat# 75-203-FL550

Size : 200uL

Contatta il distributore locale :

Telefono : +1 850 650 7790

Marca : Antibodies Incorporated

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Contatta il distributore locale :

Telefono : +1 850 650 7790

SKU: 75-203-FL550

Product Details

Target

Kir2.2 K+ channel

Target Description

ATP-sensitive inward rectifier potassium channel 12or Kir2.2 is encoded by the gene KCNJ12. Kir2.2 is a member of the inward rectifier potassium ion channel family and plays a role controlling the resting membrane potential in muscle cells and neurons. Kir2.2 is an integral membrane protein that is expressed in heart, brain and in aortic endothelial cells. In brain, Kir2.2 is expressed throughout the forebrain and cerebellum. Diseases associated with KCNJ12 include Smith-Magenis Syndrome and Leber Congenital Amaurosis 16.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N124B/38

Isotype

IgG1

Applications

ICC

Host Species

Mouse

Gene Name

Kcnj12 Irk2

Molecular Weight

48 kDa

Antigen

Synthetic peptide amino acids 390-410 (cytoplasmic C-terminus) of rat Kir2.2 (accession number P52188)

Species Reactivity

Rat

Antibody Registry ID

AB_2939753

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

Specificity

No cross-reactivity against Kir2.1 or Kir2.3

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Potassium channel, inwardly rectifying subfamily J member 12)

UniProt Details

UniProt (Human): Q14500
UniProt (Immunogen Species): P52188

Anti-Kir2.2 K+ Channel Antibody FL550 Conjugate

Cat# 75-203-FL550

Contatta il distributore locale :

Marca : Antibodies Incorporated

Contatta il distributore locale :

SKU: 75-203-FL550

Product Details

Bulk Order Anti-Kir2.2 K+ Channel Antibody FL550 Conjugate