ER81 (ETV1) (NM_004956) Human Recombinant Protein
CAT#: TP310533
Recombinant protein of human ets variant 1 (ETV1), 20 µg
Size: 100 ug 1 mg
Product Images
Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence | >RC210533 protein sequence Red=Cloning site Green=Tags(s) MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAEAQVPDNDEQF VPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTP SSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPM YQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQE GFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSN SHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEA LFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Predicted MW | 55 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_004947 |
| Locus ID | 2115 |
| UniProt ID | P50549 |
| Cytogenetics | 7p21.2 |
| Refseq Size | 6824 |
| Refseq ORF | 1431 |
| Synonyms | ER81 |
| Summary | This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2016] |
| Protein Families | ES Cell Differentiation/IPS, Transcription Factors |
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Resources
Recombinant Protein Resources |
Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| LC401540 | ETV1 HEK293T cell transient overexpression lysate (as WB positive control) | 134,00 EUR | |
| LC431330 | ETV1 HEK293T cell transient overexpression lysate (as WB positive control) | 134,00 EUR | |
| LC431362 | ETV1 HEK293T cell transient overexpression lysate (as WB positive control) | 134,00 EUR | |
| LC431376 | ETV1 HEK293T cell transient overexpression lysate (as WB positive control) | 134,00 EUR | |
| LC431397 | ETV1 HEK293T cell transient overexpression lysate (as WB positive control) | 134,00 EUR | |
| LY401540 | Transient overexpression lysate of ets variant 1 (ETV1), transcript variant 1 | 436,00 EUR | |
| LY431330 | Transient overexpression lysate of ets variant 1 (ETV1), transcript variant 7 | 436,00 EUR | |
| LY431362 | Transient overexpression lysate of ets variant 1 (ETV1), transcript variant 6 | 436,00 EUR | |
| LY431376 | Transient overexpression lysate of ets variant 1 (ETV1), transcript variant 5 | 436,00 EUR | |
| LY431397 | Transient overexpression lysate of ets variant 1 (ETV1), transcript variant 2 | 436,00 EUR | |
| PH310533 | ETV1 MS Standard C13 and N15-labeled recombinant protein (NP_004947) | 3 255,00 EUR |