GW9662 [22978-25-2]
Cat# HY-16578-1ml
Size : 10mM/1mL
Marca : MedChemExpress
GW9662 is a potent and selective PPARγ antagonist with an IC50 of 3.3 nM, showing 10 and 1000-fold selectivity over PPARα and PPARδ, respectively.
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GW9662 Chemical Structure
CAS No. : 22978-25-2
This product is a controlled substance and not for sale in your territory.
Based on 135 publication(s) in Google Scholar
Other Forms of GW9662:
- GW9662-d5 Obtenir un devis
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GW9662 purchased from MedChemExpress. Usage Cited in: Cell Rep. 2022 Nov 15;41(7):111668. [Abstract]
- GW9662 and MBPH co-treatment markedly reverse the PPARγ activation stimulated by MBPH in HepG2 cells.
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GW9662 purchased from MedChemExpress. Usage Cited in: Cell Death Differ. 2019 Nov;26(11):2253-2267. [Abstract]
- Protein expression was examined using immunoblotting with or without the treatment of GW9662.
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GW9662 purchased from MedChemExpress. Usage Cited in: Eur J Pharmacol. 2019 Jan 15;843:134-144. [Abstract]
- Protein levels of sAPPα and sAPPβ are measured by western blot assay in cerebral cortex of 12-month-old AD mice with different treatments (RSG and GW9662).
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GW9662 purchased from MedChemExpress. Usage Cited in: Eur J Pharmacol. 2019 Jan 15;843:134-144. [Abstract]
- Protein levels of BACE1 and APP are measured by western blot assay in cerebral cortex of 12-month-old AD mice with different treatments (RSG and GW9662).
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GW9662 purchased from MedChemExpress. Usage Cited in: Eur J Pharmacol. 2019 Jan 15;843:134-144. [Abstract]
- PPARγ level is determined by IF assay in 3×Tg-AD mice, 3×Tg-AD mice with RSG treatment, 3×Tg-AD-KO mice, 3×Tg-AD-KO mice with GW9662 stimulation.
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GW9662 purchased from MedChemExpress. Usage Cited in: Gene. 2018 Oct 6;682:33-41. [Abstract]
- OE-Con and OE cells are treated with GW9662 (10 μM), and protein expression levels are determined by western blot.
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GW9662 purchased from MedChemExpress. Usage Cited in: Free Radic Res. 2018 Feb;52(2):198-211. [Abstract]
- The effect of GW9662 on the protein expression of PPARγ.
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GW9662 purchased from MedChemExpress. Usage Cited in: Yonsei Med J. 2018 Nov;59(9):1096-1106. [Abstract]
- MCN and N2a cells are treated with Control (DMSO), Troglitazone (Tro; 20 µM), or GW9662 (10 µM) for 24 h, followed by detection of PPAR-γ protein level via Western blot assay.
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GW9662 purchased from MedChemExpress. Usage Cited in: Am J Transl Res. 2016 Dec 15;8(12):5169-5186. [Abstract]
- Inhibition of PPARγ by GW9662 attenuates the anti-apoptotic effect of quercetin. Western blot analysis of cleaved caspase-3 in the indicated groups.