IFNG Rabbit Polyclonal Antibody

Cat# SP2138A

Size : 500ug

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IFNG Rabbit Polyclonal Antibody

Specifications
Product Data
Application ELISA, FN, WB
Application ELISA.
Functional Assays: 10-50 µg/ml.
Western Blot:
This antibody detects a band of approximately 18 kDa.
Reactivity Chicken
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Recombinant Chicken Interferon Gamma
Specificity This antibody recognizes Chicken Interferon gamma (chIFN-gamma).
This antibody can be used to neutralize chIFN-gamma activity and to discriminate the antiviral activity of chIFNg-amma from that of chIFN-alpha and chIFN-beta.
Buffer PBS
State: Azide Free
State: Liquid purified IgG fraction
Stabilizer: None
Preservative: None
Concentration lot specific
Purification Affinity Chromatography on protein G
Conjugation Unconjugated
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name interferon, gamma
Database Link
Background Original studies investigating the properties of chicken Interferon (chIFN), revealed properties similar to mammalian IFN type I (IFNI), and it has since become apparent that there are at least three distinct chicken interferon proteins, designated as chIFN-alpha, chIFN-beta and chIFN-gamma. chIFN-gamma was first identified, when supernatant from chicken spleen cells stimulated with concanavalin A (ConA ), displayed macrophage-activating factor (MAF) activity - the principle function of mammalian type II IFNgamma. Several independent studies have since supported the existence of this chicken homolog, by the cloning of IFN-gamma cDNA from activated chicken T cells and demonstrating that recombinant chicken IFNgamma strongly upregulates the expression of MHC class II and iNOS genes.
Synonyms IFN-gamma, gamma IFN
Reference Data
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