LRP5/6 Polyclonal Antibody
Cat# bs-2905R
Size : 100ul
Marca : Bioss
LRP5/6 Polyclonal Antibody
Applications
Reactivity
Predicted Reactivity
Overview | |
Catalog # | bs-2905R |
Product Name | LRP5/6 Polyclonal Antibody |
Applications | ELISA, IHC-P, IF(IHC-P) |
Reactivity | Human, Mouse, Rat |
Predicted Reactivity | Dog, Cow, Pig, Horse, Rabbit |
Specifications | |
Conjugation | Unconjugated |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human LRP6 |
Immunogen Range | 451-550/1613 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Storage Condition | Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target | |
Gene ID | 4040, 4041 |
Subcellular location | Cytoplasm, Cell membrane |
Synonyms | ADCAD2; C030016K15Rik; Cd; FLJ90062; FLJ90421; Low density lipoprotein receptor related protein 6; LRP6_HUMAN; Low-density lipoprotein receptor-related protein 6; low-density lipoprotein receptor-related protein 6 precursor; LRP-6; LRP-5; LR3; LRP7; Low-density lipoprotein receptor-related protein 5. |
Background | This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009]. |
Application Dilution | |
ELISA | 1:500-1000 |
IHC-P | 1:200-400 |
IF(IHC-P) | 1:50-200 |