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Cat# AM08392PU-N
Size : 50ug
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| Product Data | |
| Clone Name | 6D499 |
|---|---|
| Application | FC, IHC |
| Application | Flow Cytometry. Immunohistochemistry on Paraffin Sections: 2.5 - 5 µg/ml. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Clonality | Monoclonal |
| Immunogen | L1.2 cells expressing Human Interleukin-8 Receptor type B (IL8RB). |
| Specificity | This antibody recognizes Interleukin 8 Receptor B (CXCR2/IL8RB). |
| Buffer | PBS without preservatives. State: Purified State: Liquid purified Ig fraction |
| Concentration | lot specific |
| Purification | Protein G Chromatography. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (Add 40-50% Glycerol) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Gene Name | C-X-C motif chemokine receptor 2 |
| Database Link | |
| Background | CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family (subfamily, chemokine). Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries. |
| Synonyms | CXCR2, CXCR-2, GRO/MGSA receptor, IL-8 receptor type 2, CDw128b, IL8 receptor beta |
| Reference Data | |
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