ViralBoost Reagent
Cat# VB100
Size : 1mL
Marca : Alstem
ViralBoost Reagent
Highlights:
- Regulates packaging in transcriptional level
- Works for both lenti-and retro-viral packaging
- Increases viral particle production up to 10-fold
- Achieve high titer at low cost
- Novel cocktail of small molecules
- Easy to use
Description:
ViralBoost Reagent (500X) is a novel cocktail of small molecules that is used for high titer virus production and is a powerful, broadly applicable reagent for effective virus packaging. It stably regulates the viral RNA packaging on the transcriptional level, which can greatly enhance production of either retro- or lenti-viral particles up to 10 fold. The easy-to-use protocol makes ViralBoost Reagent well-suited for various scales of virus packaging.
Specifications:
Product Name | ViralBoost Reagent |
---|---|
Shipping Condition | Room Temperature - 2 Day Shipping |
Storage and Stability | Store at 4 °C. This product is stable for 12 months when stored as directed. |
Quality Control | Each lot is functionally tested in transfection assays using 293T cells. |
Restricted Use | For Research Use Only. Not for use in diagnostic or therapeutic procedures. |
I. Hollerer et al., Evidence for an Integrated Gene Repression Mechanism based on mRNA Isoform Toggling in Human Cells. G3:Genes/Genomes/Genetics (2019).
- H. Ishii et al., miR-130a and miR-145 reprogram Gr-1+CD11b+ myeloid cells and inhibit tumor metastasis through improved host immunity. Nat Commun 9, (2018).
- E. Shifrut et al., Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function. Cell 175, (2018).
- J. Udeochu et al., Exosome release promotes inflammatory resolution in activated and aged microglia. bioRxiv, (2018).
- Z. Yang et al., Expression of Exogenous Genes in Murine Primary B Cells and B Cell Lines Using Retroviral Vectors. Methods Mol Biol 1707, (2018).
- T. Roth et al., Reprogramming human T cell function and specificity with non-viral genome targeting. Nature (2018)
- G. Smith et al., IL-2Rβ abundance differentially tunes IL-2 signaling dynamics in CD4+ and CD8+ T cells. Sci Signaling 10, (2017).
- Z Yang et al. Regulation of B cell fate by chronic activity of the IgE B cell receptor. eLife (2016).