AG Scientific
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AG Scientific è specializzata in metaboliti secondari derivati dalla fermentazione. La maggior parte dei prodotti è costituita da antibiotici per la selezione genica, ma il catalogo comprende anche reagenti antimicrobici, antimicotici, antitumorali, antivirali, antiparassitari e immunosoppressori.
Antibiotici:
AG Scientific, Inc. ha sviluppato una serie di agenti di screening antibiotico, tra cui Blasticidin S, G-418, Puromicina, Gentamicina, Kanamicina, Ampicillina, Streptomicina, Carbenicillina.
Più recentemente, AG Scientific ha stretto una partnership con clienti farmaceutici che utilizzano la tecnologia CRISPR.
Antitumorale:
Il catalogo comprende metaboliti secondari nel campo del cancro come rapamicina, FK-506, ciclosporina A.
Sito web: www.agscientific.com
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SARS-CoV-2 - Prazosine - Therapeutic Candidates
Prazosin is an antihypertensive derived from quinazoline which belongs to the class of alpha-blockers. Prazosin is used to lower blood pressure by relaxing blood vessels. This action is due to the fact that prazosin is selective for alpha1 receptors on vascular smooth muscle. These receptors are responsible for the vasoconstrictive action of norepinephrine, which is responsible for raising blood pressure. Because of these effects, prazosin is indicated in the treatment of high blood pressure, anxiety and post-traumatic stress disorder and panic disorder.
A clinical study has begun to determine the potential of prazosin to slow and possibly prevent one of the worst effects of Covid-19, cytokine storm. This study was based on research in mice that showed that prazosin could prevent this cytokine storm phenomenon, as well as a study of a cohort of patients suffering from acute respiratory distress from a variety of causes.
Risultati della ricerca : 1 prodotto(i) trovato(i)
Limita la ricerca :
RUOCE / IVD
- Inhibitor/Antagonist/Agonist 1
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