SARS-CoV-2 - Spike protein - Primary antibodies
The SARS-CoV-2 virus, the cause of the current Covid-19 pendemia, can infect human respiratory epithelial cells through an interaction with the human ACE2 receptor or angiotensin converting enzyme receptor 2. SARS-CoV-2 has on its surface a protein called Spike or S protein. This type I transmembrane protein is present on the viral envelope in the form of a homotrimer. Each monomer consists of 2 subunits, S1 and S2. The S1 subunit contains a receptor binding domain (RBD) which binds to the ACE2 receptor on the host membrane. The S2 sub-unit is activated by the bond between S1 and the ACE2 receptor and contains the elements necessary for membrane fusion. The S protein thus plays an important role in the infection of SARS-CoV-2 as well as in the induction of neutralizing antibody and T cell responses and in protective immunity.
Risultati della ricerca : 2767 prodotto(i) trovato(i)
Limita la ricerca :
RUOCE / IVD
- Unconjugated 1970
- Biotin 87
- HRP 65
- FITC 20
- PE 4
- Gold 1
- virus 1647
- human 150
- mouse 76
- rabbit 8
- monkey 4
- all species 3
- Primary antibody
- rabbit 964
- mouse 594
- human 491
- goat 26
- chicken 8
- yeast 6
- llama 5
- monkey 5
- plant 2
- sars-cov-2 2
- sheep 2
- rat 1
- virus 1
- ELISA 2154
- WB 906
- IF 317
- Neutralization 185
- IP 140
- FC 127
- IHC 124
- ICC 123
- Assay 45
- Dot blot 26
- Chemiluminescence 18
- FA 10
- Immunoassay 8
- Lateral Flow 8
- Blocking 3
- Chromatography 2
- Detection 2
- Microscopy 2
- Monoclonal 636
- Polyclonal 552
- CR3022 38
- S 31
- 2B-E7-C9 26
- 2B-G10-A1 26
- AM122 18
- D001 18
- A1 15
- D004 14
- H6 13
- D006 11
- 5D9 10
- AM130 10
- CB6 10
- D003 10
- DM24 10
- DM25 10
- 7 9
- DM39 9
- DM40 9
- DM41 9
- 5E8 8
- RH-01 8
- RH-02 8
- 2146 7
- 2165 7
- 2196 7
- ABM19C9 7
- MAbs in vitro: R107 7
- MAbs in vivo: RBD1106 7
- OTI1H6 7
- OTI5A7 7
- R007 7
- RBD1125 7
- 118 6
- 43 6
- D005 6
- DM26 6
- DM27 6
- DM35 6
- DM42 6
- 16-F-28 5
- 19-J-16 5
- 1H2 5
- 23-D-12 5
- 27B12 5
- 38G5 5
- 49F9 5
- 4A3 5
- 5A7 5
- 6G7 5
- 71D2 5
- 79C3 5
- AM001414 (414-1) 5
- AM002414 (414-2) 5
- AM004414 (414-4) 5
- AM043105 (105-43) 5
- OTI1C2 5
- R00231-234 5
- R00240-242 5
- R00244-246 5
- R00247-250 5
- R00251-254 5
- R00263-266 5
- R00267-270 5
- R00271-274 5
- R00319-322 5
- R00323-326 5
- R00327-330 5
- R00331-334 5
- Recombinant 5
- 1B2 4
- 1G8D11 4
- 27C2 4
- 28H3 4
- 30C5 4
- 36A7 4
- 58F8 4
- 5E12 4
- 5H4C5 4
- 72A5 4
- 7A4D12 4
- 7C11H11 4
- 9F7E4 4
- ABM5D1.1E8 4
- AD10.F6.G3.E3 4
- AS35 4
- DM54 4
- DM55 4
- M89079 4
- 001 3
- 003 3
- 05 3
- 1 3
- 1.6C7 3
- 117 3
- 135 3
- 17 3
- 18C7B10 3
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