Angene
![]() |
||
Angene si impegna a fornire prodotti chimici di qualità da utilizzare nella ricerca e sviluppo e nella produzione commerciale. Angene offre oltre 100.000 prodotti tra cui reagenti di laboratorio, building blocks, intermedi, prodotti sfusi, prodotti agrochimici, ingredienti naturali e principi attivi farmaceutici (API). Oltre agli oltre 100.000 prodotti, Angene offre sintesi personalizzate di sostanze chimiche non disponibili in commercio.
Sito web: www.angenechemical.com
|
![SARS-CoV-2 - Telmisartan - Therapeutic Candidates](https://www.clinisciences.com/it/upload/thumbs/therapeutic-covid-19-t4dswy-423073.jpg)
SARS-CoV-2 - Telmisartan - Therapeutic Candidates
Telmisartan is an angiotensin II inhibitor. It blocks the action of angiotensin II through its antagonistic function on the receptors for this substance naturally present in the body, which causes contraction of the arteries and increases arterial pressure. Telmisartan is therefore an antihypertensive drug used in the treatment of high blood pressure and chronic renal failure. Telmisartan has several advantages: its half-life is 24 hours (longer than other angiotensin II receptor antagonists) and it does not alter the metabolism of bradykinin (unlike ACE inhibitors), which avoids associated side effects such as coughing.
Studies have shown that during SARS-Cov-6 infection, alveolar cell ACE2 protein is targeted. The loss of the enzymatic action of ACE2 leads to an increase in the concentration of angiotensin II. This would be the starting point for the cytokine storm described in the most affected Covid-19 patients. For this reason, clinical studies have been initiated to test the effect of telmisartan on the development of acute respiratory distress syndrome (ARDS) in Covid-19 patients.
Risultati della ricerca : 0 prodotto(i) trovato(i)
Limita la ricerca :
RUOCE / IVD
Cat#
Descrizione
Cond.
Priced
‹
›