Biorbyt

Products for advancing your discoveries

 
From antibodies to proteins, biochemicals to ELISA kits, Biorbyt's high quality research products are available for you to enable world class research and contribution to a deeper understanding of life sciences.
 
A comprehensive catalog of life science research products covering the areas of Neuroscience, Signal transduction, Cell Biology, Cancer Metabolism, Cardiovascular and others
 
Product range :
 
  • Antibodies
Choose from over 100,000 primary antibodies and over 2,000 secondary antibodies. Monoclonals and polyclonals tested in a number of applications - WB, ELISA, IHC, FACS and many more.
 
  • Proteins
Choose from over 7,000 proteins and over 400 active proteins. All of our proteins have been validated for use in ELISAs, WB and IHC-P
 
  • Biochemicals
We have over 10,000 biochemicals for use in your research.
 
  • ELISA kits
We have over 2,000 ELISA kits covering many research areas . Each kit comes with a fully detailed protocol and examples of expected results.
 
 
 
SARS-CoV-2 - Spike protein - Primary antibodies

SARS-CoV-2 - Spike protein - Primary antibodies


The SARS-CoV-2 virus, the cause of the current Covid-19 pendemia, can infect human respiratory epithelial cells through an interaction with the human ACE2 receptor or angiotensin converting enzyme receptor 2. SARS-CoV-2 has on its surface a protein called Spike or S protein. This type I transmembrane protein is present on the viral envelope in the form of a homotrimer. Each monomer consists of 2 subunits, S1 and S2. The S1 subunit contains a receptor binding domain (RBD) which binds to the ACE2 receptor on the host membrane. The S2 sub-unit is activated by the bond between S1 and the ACE2 receptor and contains the elements necessary for membrane fusion. The S protein thus plays an important role in the infection of SARS-CoV-2 as well as in the induction of neutralizing antibody and T cell responses and in protective immunity.

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