alpha-SMA (ACTA2, AAT6, ACTSA, MYMY5, Actin, aortic Smooth Muscle, Alpha-Actin-2, Cell Growth-inhibiting Gene 46 Protein, alpha-SMA, a-SMA, aSMA, SMA-alpha,)

Cat# 220701-50ul

Size : 50ul

Marca : US Biological

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220701 alpha-SMA (ACTA2, AAT6, ACTSA, MYMY5, Actin, aortic Smooth Muscle, Alpha-Actin-2, Cell Growth-inhibiting Gene 46 Protein, alpha-SMA, a-SMA, aSMA, SMA-alpha,)

Clone Type
Polyclonal
Host
rabbit
Source
human
Swiss Prot
P62736
Isotype
IgG
Grade
Affinity Purified
Applications
IF IHC WB
Crossreactivity
Hu Mo Rt
Shipping Temp
Blue Ice
Storage Temp
-20°C

Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. AATs are characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.||Applications: |Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry. Other applications not tested.||Recommended Dilutions:|Western Blot: 1:1000|Immunohistochemistry: 1:50-1:200|Immunofluorescence: 1:50-1:200|Optimal dilutions to be determined by the researcher.||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Applications
Product Type: Pab|Isotype: IgG|Host: rabbit|Source: human|Concentration: ~1mg/ml|Form: Supplied as a liquid PBS, pH 7.2, 0.02% sodium azide, 50% glycerol|Purity: Purified by immunoaffinity chromatography|Immunogen: Full length recombinant protein corresponding to human α-SMA.|Specificity: Recognizes endogenous levels of human alpha-SMA. Species Crossreactivity: mouse and rat||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Full length recombinant protein corresponding to human α-SMA.
Form
Supplied as a liquid PBS, pH 7.2, 0.02% sodium azide, 50% glycerol
Purity
Purified by immunoaffinity chromatography
Specificity
Recognizes endogenous levels of human alpha-SMA. Species Crossreactivity: mouse and rat

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