Anti-ACTN2 antibody (C-Term)

Clonality:	Monoclonal
Conjugation:	Unconjugated
Formulation:	Liquid in 0.1M Tris-Glycine (pH7.4, 150 mM NaCl) , 0.2% Sodium Azide and 50% Glycerol.
Purification:	Affinity purification
Concentration:	1 mg/mL
Dilution Range:	WB 1:1000-1:2000 IF 1:100-1:500
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ACTN2
Gene ID:	88
Uniprot ID:	ACTN2_HUMAN
Immunogen Region:	C-Term
Specificity:	Actinin-Alpha 2 Monoclonal Antibody detects endogenous levels of Actinin-Alpha 2 protein.
Immunogen:	Purified recombinant human Actinin-Alpha 2 (C-terminus) protein fragments expressed in E.coli.

Post Translational Modifications	Ubiquitinated by FBXL22, leading to proteasomal degradation.
Function	F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Protein Name	Alpha-Actinin-2 Alpha-Actinin Skeletal Muscle Isoform 2 F-Actin Cross-Linking Protein
Database Links	Reactome: R-HSA-114608 Reactome: R-HSA-373753 Reactome: R-HSA-390522 Reactome: R-HSA-438066 Reactome: R-HSA-442982 Reactome: R-HSA-5673001 Reactome: R-HSA-9609736 Reactome: R-HSA-9617324 Reactome: R-HSA-9620244
Cellular Localisation	Cytoplasm Myofibril Sarcomere Z Line Colocalizes With Myoz1 And Flnc At The Z-Lines Of Skeletal Muscle
Alternative Antibody Names	Anti-Alpha-Actinin-2 antibody Anti-Alpha-Actinin Skeletal Muscle Isoform 2 antibody Anti-F-Actin Cross-Linking Protein antibody Anti-ACTN2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance