Reagenti e strumenti per immunologia, biologia cellulare e biologia molecolare

Anti-GABA-A-R, Beta1 Antibody FL650 Conjugate

Stampa

Cat# 75-137-FL650

Size : 200uL

Contatta il distributore locale :

Telefono : +1 850 650 7790

Marca : Antibodies Incorporated

Richiedere ulteriori informazioni

Contatta il distributore locale :

Telefono : +1 850 650 7790

SKU: 75-137-FL650

Product Details

Target

GABA(A)R, Beta1

Target Description

Gamma-aminobutyric acid receptor subunit beta-1 or -GABA AR-Beta1 is encoded by the gene GABRB1 GABAA receptors are members of the Cys-loop family of ligand-gated ion channels. GABA AR alpha 5 is a subunit of the pentameric GABA receptors where GABA is the major inhibitory neurotransmitter in the vertebrate brain and mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel. GABA AR-Beta1 is primarily expressed in brain at the cell junction, synapse,and the postsynaptic cell membrane. Diseases associated with GABRB1 include early infantile epileptic encephalopathy 43, neurotic disorder, schizophrenia and autism.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N96/55

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Gabrb1

Molecular Weight

55 kDa

Antigen

Fusion protein amino acids 327-450 of mouse GABA-A-R-Beta1 (accession number P50571) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939511

Storage

Aliquot and store at -8% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

Specificity

No cross-reactivity against GABA-A-R-Beta2 or -Beta3

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Gamma-aminobutyric acid receptor subunit beta-1 (GABA(A) receptor subunit beta-1)

UniProt Details

UniProt (Human): P18505
UniProt (Immunogen Species): P50571

Anti-GABA-A-R, Beta1 Antibody FL650 Conjugate

Cat# 75-137-FL650

Contatta il distributore locale :

Marca : Antibodies Incorporated

Contatta il distributore locale :

SKU: 75-137-FL650

Product Details

Bulk Order Anti-GABA-A-R, Beta1 Antibody FL650 Conjugate