Bovine Type I Collagen-Solution
Cat# 1200-02S
Size : 0.5mg
Marca : Southern Biotech
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Telefono : +1 850 650 7790
| Description | Collagen is the main structural protein in the extracellular space and is the most abundant protein in the ECM. Collagens are divided into two classes - fibril (types I, II, III, V) and non-fibril (types IV, VI). Type I collagen is the most abundant collagen and is expressed in almost all connective tissues including skin, tendon, and bone tissue. It is also the predominant component of the interstitial matrix. Type I collagen mutations are associated in a range of diseases including osteogenesis imperfecta and Ehlers–Danlos syndrome. Type I collagen consists of two α1(I) chains and one α2(I) chain. |
|---|---|
| Source | Placental villi |
| Purity | > 90% by SDS-PAGE |
| Purification Method | Controlled and limited pepsin digestion followed by selective salt precipitation |
| Buffer Formulation | 500 mM acetic acid |
| Concentration | 0.5 mg/mL |
| Volume | 1.0 mL |
| Recommended Storage | 2-8°C |
| Applications | ELISA – Quality tested SDS-PAGE – Quality tested Surface Plasmon Resonance – Reported in literature 2 Coating Material for – Adhesion Studies – Reported in literature 1-3 Migration Studies – Reported in literature 4 |
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- 1. Switalski LM, Butcher WG, Caufield PC, Lantz MS. Collagen mediates adhesion of Streptococcus mutans to human dentin. Infect Immun. 1993;61:4119-25. (Coating, Adhesion Studies)
- 2. House-Pompeo K, Boles JO, Höök M. Characterization of bacterial adhesin interactions with extracellular matrix components utilizing biosensor technology. Methods. 1994;6:134-42. (SPR, Coating, Adhesion Studies)
- 3. McGrady JA, Butcher WG, Beighton D, Switalski LM. Specific and charge interactions mediate collagen recognition by oral lactobacilli. J Dent Res. 1995;74:649-57. (Coating, Adhesion Studies)
- 4. Augustin-Voss HG, Pauli BU. Quantitative analysis of autocrine-regulated, matrix-induced, and tumor cell-stimulated endothelial cell migration using a silicon template compartmentalization technique. Exp Cell Res. 1992;198:221-7. (Coating, Migration Studies)