CD95 Polyclonal Antibody
Cat# bs-0215R-20ul
Size : 20ul
Marca : Bioss
CD95 Polyclonal Antibody
Applications
Reactivity
Overview | |
Catalog # | bs-0215R |
Product Name | CD95 Polyclonal Antibody |
Applications | WB, ELISA, FCM, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC) |
Reactivity | Human, Mouse, Rat, Monkey |
Specifications | |
Conjugation | Unconjugated |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from mouse FAS |
Immunogen Range | 35-110/327 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Storage Condition | Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target | |
Gene ID | 14102 |
Swiss Prot | P25446 |
Subcellular location | Secreted, Cell membrane |
Synonyms | lpr; APO1; APT1; CD95; TNFR6; Tnfrsf6; AI196731; Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; Fas |
Background | Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity). |
Application Dilution | |
WB | 1:300-5000 |
ELISA | 1:500-1000 |
FCM | 1:20-100 |
IHC-P | 1:200-400 |
IHC-F | 1:100-500 |
IF(IHC-P) | 1:50-200 |
IF(IHC-F) | 1:50-200 |
IF(ICC) | 1:50-200 |