Hexokinase 1, NT (Hexokinase-1, Hexokinase Type I, HEX1, HK I, HKI, HK1, HXK1, Brain Form Hexokinase) (PE)
Cat# H2035-25N-PE-200ul
Size : 200ul
Marca : US Biological
H2035-25N-PE Rabbit Anti-Hexokinase 1, NT (Hexokinase-1, Hexokinase Type I, HEX1, HK I, HKI, HK1, HXK1, Brain Form Hexokinase) (PE)
Clone Type
PolyclonalHost
rabbitSource
humanSwiss Prot
P19367Isotype
IgGGrade
Affinity PurifiedApplications
FLISA IHC WBCrossreactivity
Hu RtShipping Temp
Blue IceStorage Temp
4°C Do Not FreezeHexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. The hexokinase gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of the hexokinase gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. HK1 encodes the ubiquitously expressed isoform. Its 5' end includes an exon which is unique to this transcript and which encodes a distinct N-terminus that contains the porin binding domain (PBD). The porin binding domain mediates association with the mitochondrial membrane.||Applications: |Suitable for use in FLISA, Western Blot and Immunohistochemistry. Other applications not tested.||Recommended Dilutions:|Immunohistochemistry: Paraffin sections|Optimal dilutions to be determined by the researcher.||Storage and Stability:|Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.||Note: Applications are based on unconjugated antibody.