Kinetin [525-79-1]
Cat# HY-N0160-10g
Size : 10g
Marca : MedChemExpress
Kinetin (N6-furfuryladenine) belongs to the family of N6-substituted adenine derivatives known as cytokinins, which are plant hormones involved in cell division, differentiation and other physiological processes. Kinetin has anti-aging effects.
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Kinetin Chemical Structure
CAS No. : 525-79-1
This product is a controlled substance and not for sale in your territory.
Based on 5 publication(s) in Google Scholar
Description |
Kinetin (N6-furfuryladenine) belongs to the family of N6-substituted adenine derivatives known as cytokinins, which are plant hormones involved in cell division, differentiation and other physiological processes. Kinetin has anti-aging effects[1]. |
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In Vitro |
Kinetin (N6-furfuryladenine) shows to have a direct effect on superoxide dismutase activity in plants; prevent oxidation of unsaturated acids in plant membranes; slow down development and aging in insects, by reducing their fecundity and increasing the specific activity of catalase; and delay the onset of many age-related characteristics that appear in normal human skin fibroblasts undergoing aging in vitro. Kinetin (70-150 μM) markedly suppressed hydroxyl radical formation by about 41% and 76%, respectively[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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In Vivo |
Kinetin (N6-furfuryladenine) (2-6 mg/kg; injection into the tail vein) effectively prevents ADP-induced acute pulmonary thrombosis in mice[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Essai clinique |
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Masse moléculaire |
215.21 |
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Formule |
C10H9N5O |
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CAS No. |
525-79-1 |
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Appearance |
Solid |
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Color |
White to light yellow |
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SMILES |
C12=NC=NC(NCC3=CC=CO3)=C1N=CN2 |
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Structure Classification |
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Initial Source |
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Livraison | Room temperature in continental US; may vary elsewhere. |
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Stockage |
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Solvant et solubilité |
In Vitro:
DMSO : 33.33 mg/mL (154.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) 1M NaOH : 33.33 mg/mL (154.87 mM; Need ultrasonic) H2O : < 0.1 mg/mL (insoluble) Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO
+
%
+
%
Tween-80
+
%
Saline
The co-solvents required include: DMSO,
. All of co-solvents are available by MedChemExpress (MCE).
, Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration:
mg/mL
Method for preparing stock solution:
mg
drug dissolved in
μL
DMSO (Stock solution concentration: mg/mL).
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take
μL DMSO stock solution, add
μL .
μL , mix evenly, next add
μL Tween 80, mix evenly, then add
μL Saline.
If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
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Pureté et documentation |
Purity: 99.47% |
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Références |
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Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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DMSO / 1M NaOH | 1 mM | 4.6466 mL | 23.2331 mL | 46.4662 mL | 116.1656 mL |
5 mM | 0.9293 mL | 4.6466 mL | 9.2932 mL | 23.2331 mL | |
10 mM | 0.4647 mL | 2.3233 mL | 4.6466 mL | 11.6166 mL | |
15 mM | 0.3098 mL | 1.5489 mL | 3.0977 mL | 7.7444 mL | |
20 mM | 0.2323 mL | 1.1617 mL | 2.3233 mL | 5.8083 mL | |
25 mM | 0.1859 mL | 0.9293 mL | 1.8586 mL | 4.6466 mL | |
30 mM | 0.1549 mL | 0.7744 mL | 1.5489 mL | 3.8722 mL | |
40 mM | 0.1162 mL | 0.5808 mL | 1.1617 mL | 2.9041 mL | |
50 mM | 0.0929 mL | 0.4647 mL | 0.9293 mL | 2.3233 mL | |
60 mM | 0.0774 mL | 0.3872 mL | 0.7744 mL | 1.9361 mL | |
80 mM | 0.0581 mL | 0.2904 mL | 0.5808 mL | 1.4521 mL | |
100 mM | 0.0465 mL | 0.2323 mL | 0.4647 mL | 1.1617 mL |
Kinetin Related Classifications
- Neurological Disease
- Immunology/Inflammation
- SOD