PSMA I&S (TFA)
Cat# HY-148152A-5mg
Size : 5mg
Marca : MedChemExpress
PSMA I&S (TFA) is a precursor of the 99mTc-labeled PSMA-targeting ligand.
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PSMA I&S TFA Chemical Structure
This product is a controlled substance and not for sale in your territory.
Based on 1 publication(s) in Google Scholar
Other Forms of PSMA I&S TFA:
- PSMA I&S Obtenir un devis
Description |
PSMA I&S (TFA) is a precursor of the 99mTc-labeled PSMA-targeting ligand[1]. |
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Masse moléculaire |
1413.43 |
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Formule |
C61H83F3N10O23S |
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Appearance |
Solid |
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Color |
White to off-white |
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SMILES |
OC(C=C1)=CC=C1C[C@@H](NC([C@@H](CO)NC([C@@H](CO)NC([C@@H](CO)NC(CS)=O)=O)=O)=O)C(N[C@@H](C(N[C@@H](C(O)=O)CCCCNC(CCCCCCC(NCCCC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)=O)=O)CC2=CC3=C(C=CC=C3)C=C2)=O.OC(C(F)(F)F)=O |
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Livraison | Room temperature in continental US; may vary elsewhere. |
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Stockage |
-20°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen) |
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Solvant et solubilité |
In Vitro:
DMSO : 100 mg/mL (70.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO
+
%
+
%
Tween-80
+
%
Saline
The co-solvents required include: DMSO,
. All of co-solvents are available by MedChemExpress (MCE).
, Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration:
mg/mL
Method for preparing stock solution:
mg
drug dissolved in
μL
DMSO (Stock solution concentration: mg/mL).
*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take
μL DMSO stock solution, add
μL .
μL , mix evenly, next add
μL Tween 80, mix evenly, then add
μL Saline.
If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
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Pureté et documentation | |||||||||||||
Références |
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Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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DMSO | 1 mM | 0.7075 mL | 3.5375 mL | 7.0750 mL | 17.6875 mL |
5 mM | 0.1415 mL | 0.7075 mL | 1.4150 mL | 3.5375 mL | |
10 mM | 0.0707 mL | 0.3537 mL | 0.7075 mL | 1.7687 mL | |
15 mM | 0.0472 mL | 0.2358 mL | 0.4717 mL | 1.1792 mL | |
20 mM | 0.0354 mL | 0.1769 mL | 0.3537 mL | 0.8844 mL | |
25 mM | 0.0283 mL | 0.1415 mL | 0.2830 mL | 0.7075 mL | |
30 mM | 0.0236 mL | 0.1179 mL | 0.2358 mL | 0.5896 mL | |
40 mM | 0.0177 mL | 0.0884 mL | 0.1769 mL | 0.4422 mL | |
50 mM | 0.0141 mL | 0.0707 mL | 0.1415 mL | 0.3537 mL | |
60 mM | 0.0118 mL | 0.0590 mL | 0.1179 mL | 0.2948 mL |
PSMA I&S TFA Related Classifications
- Immunology/Inflammation
- PSMA