Izotop
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Fondée en 1959, l'Institut des isotopes de l'Académie hongroise des sciences a commencé à produire des isotopes radioactifs en 1964. Il est devenu un centre hongrois majeur pour la recherche, le développement et la production de radio-isotopes. À partir de 1993, une partie de l'ancien Institut est devenu Institute of Isotopes Co., Ltd. (IZOTOP).
L'Institut des Isotopes Co., Ltd (Izotop) fait de la recherche, du développement et de la production d'une grande variété d'isotopes radioactifs et d'autres produits pour une large gamme de domaines d'application, en particulier les soins de santé, la recherche et l'industrie.
Site internet : www.izotop.hu
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Iode-125 radiolabeled compounds
Iodine possesses 37 known isotopes of mass number varying between 108 and 144 and 16 nuclear isomers. Of these isotopes, only iodine-127 (I-127) is stable and represents all of the natural iodine.
Of the 30 iodine radioisotopes, the most stable is iodine-129 (I-129) with a half-life of 15.7 million years. All others have a half-life of less than 60 days. Four of them are used as radiogenic tracers and therapeutic agents: I-123, I-124, I-125 and I-131.
Because iodine is absorbed by the thyroid, iodine radioisotopes are widely used in medical imaging (iodine-131 in particular) or to destroy thyroid dysfunctional tissues or other types of absorbent tissue Selectively, iodine-131-containing radiopharmaceuticals. Iodine 125 is the only other radioisotope of iodine used in radiotherapy.
Iodine 125 (I-125) is the isotope of iodine whose nucleus consists of 53 protons and 72 neutrons. It is an electron-disrupting radioisotope in Tellure 125 (Te-125) with a half-life of 59.4 days. As iodine 123 is a gamma ray emitter.
Because of its relatively long half-life and low-energy photon emission that can be detected by gamma-ray counters, Iodine 125 (I-125) is the isotope used for labeling antibodies in Radioactive immunoassays and other gamma-ray counting procedures involving in vitro proteins. The same characteristics make this isotope a useful tool for brachytherapy.
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- [125I] 92
- human 61
- rat 17
- rabbit 9
- sheep 7
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- bird 5
- mouse 2
- fish 1
- monkey 1
- Radiochemicals
- human 61
- rat 17
- rabbit 9
- sheep 7
- cow 6
- goat 6
- horse 6
- pig 6
- bird 5
- mouse 2
- fish 1
- monkey 1
- Radioimmunoassay 62
- Immunoradiometric assay 30
- monoclonal 6
- polyclonal 2
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