Our Anti-Fig4/Sac3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N202/7. It is KO validated, detects human and mouse Fig4/Sac3, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
Polyphosphoinositide phosphatase, SAC Domain-Containing Protein 3 or Fig4/Sac3 is encoded by the gene FIG4. Fig4/Sac3. The hydrolyzing phosphoinositide signals is involved with cell processes including intracellular membrane trafficking, exocytosis, endocytosis and membrane transport. Fig4/Sac3 is found widely in tissues. Diseases associated with this gene include Polymicrogyria, Yunis-Varon Syndrome and Charcot-Marie-Tooth Disease.
Purified by Protein A chromatography
0.5 mg/mL
Monoclonal
N202/7
IgG1
ICC, IHC
Mouse
Fig4 Kiaa0274 Sac3
100 kDa
Fusion protein amino acids 688-907 of mouse Sac3 (accession number Q91WF7) produced recombinantly in E. Coli
Human, Mouse
AB_2939746
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL594 Ex: 594 nm, Em: 615 nm
No cross-reactivity reported
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.