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> Camostat Mesilate

Camostat Mesilate

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Referentie M2487-10mg

Formaat : 10mg

Merk : AbMole Bioscience

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All AbMole products are for research use only, cannot be used for human consumption.

Camostat Mesilate Structure
Synonym:

FOY-305; Camostat mesylate; FOY-S980

Quality Control & Documentation
Biological Activity

Camostat is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase.

Chemical Information
Molecular Weight 494.52
Formula C20H22N4O5.CH4O3S
CAS Number 59721-29-8
Solubility (25°C) DMSO 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Serap Şimşek-Yavuz, et al. An update of anti-viral treatment of COVID-19

[2] Peter Breining, et al. Camostat mesylate against SARS-CoV-2 and COVID-19-Rationale, dosing and safety

[3] Dwight L McKee, et al. Candidate drugs against SARS-CoV-2 and COVID-19

[4] Yoshiharu Uno. Camostat mesilate therapy for COVID-19

[5] Markus Hoffmann, et al. SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor