CD1a (CD1, CD1A Antigen, Cortical Thymocyte Antigen CD1A, Epidermal Dendritic Cell Marker CD1a, FCB 6, HTA1, T Cell Surface Antigen Leu 6, Cell Surface Antigen T6, T Cell Surface Antigen T6/Leu 6, T Cell Surface Glycoprotein CD1A, T6, Thymocyte Antigen CD1A) (APC)

CD1a is a ~49kDa single pass type 1 transmembrane glycoprotein containing a single Ig-like domain, expressed in association with beta 2 microglobulin. CD1a is expressed strongly by cortical thymocytes, and also by Langerhans cells and interdigitating cells. CD1a is involved in the presentation of lipids and glycolipids to NK cells.||Applications:|Suitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested. ||Recommended Dilution:|Flow Cytometry: 10ul labels 10e6 cells in 100ul|Immunohistochemistry: Frozen sections|Optimal dilutions to be determined by the researcher. ||Hybridoma: |NS1/Ag4.1 myeloma cells with spleen cells from Balb/c mice.||Positive Control for Immunohistochemistry:|Skin||Storage and Stability:|Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. ||Note: Applications are based on unconjugated antibody.