CD3 antibody [CD3-12] (FITC)
Referentie GTX43629-25ug
Formaat : 25ug
Merk : GeneTex
Host | Rat |
---|---|
Clonality | Monoclonal |
Clone Name | CD3-12 |
Isotype | IgG1 |
Application | FACS |
Reactivity | Human, Mouse, Rabbit, Bovine, Cat, Dog, Chicken, Pig, Alpaca, Amazon Parrot, Bullfrog, Cynomolgus monkey, Duck, Great horned owl (Bubo virginianus), Harbour Porpoise, Horse, Koala, Raccoon, Rhesus Monkey, Sea Lion, Spotted Hyena, Xenopus |
Package | 25 μg |
View product citations for antibody GTX43629 on CiteAb
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application | Recommended Dilution |
---|---|
FACS | 1:50-1:100 |
Note : FACSMembrane permeabilization is required for this application. |
Not tested in other applications.
Product Note
This antibody raised against a peptide representing an invariant cytoplasmic sequence within the CD3ε chain recognizes human CD3ε.
PROPERTIES
Form
Liquid
Buffer
PBS, 1% BSA
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Protect from light.
Concentration
0.1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic peptide sequence derived from cytoplasmic epitope of CD3 (Glu-Arg-Pro-Pro-Pro-Val-Pro-Asn-Pro-Asp-Tyr-Glu-Pro-Cys) (ERPPPVPNPDYEPC )
Purification
Protein G purified
From tissue culture supernatant
From tissue culture supernatant
Conjugation
Fluorescein isothiocyanate (FITC)
RRID
AB_11169769
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
T3E Antibody , TCRE Antibody , CD3e molecule, epsilon (CD3-TCR complex) Antibody , CD3E Antibody
Background
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
Application Reference
Zhang L et al. Mol Cell Probes 2018; 41 : 43-51 Immunopotentiating effect of Inonotus obliquus fermentation products administered at vaccination in chickens.
Sun F et al. PLoS One 2016; 11 (8) : e0160659 Regulation of Nutritional Metabolism in Transition Dairy Cows: Energy Homeostasis and Health in Response to Post-Ruminal Choline and Methionine.
Application : FACS
Reactivity : Bovine
REVIEW
Application Reference
Zhang L et al. Mol Cell Probes 2018; 41:43-51 Immunopotentiating effect of Inonotus obliquus fermentation products administered at vaccination in chickens.
Sun F et al. PLoS One 2016; 11 (8):e0160659 Regulation of Nutritional Metabolism in Transition Dairy Cows: Energy Homeostasis and Health in Response to Post-Ruminal Choline and Methionine.
Application : FACS
Reactivity : Bovine
SDS | |
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PBS.pdf | |
Sodium Azide.pdf |
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