Chicken TCRyd Antibody : Biotin
Referentie OASB02396
Formaat : 0.5mg
Merk : Aviva Systems Biology
Datasheets/Manuals | Printable datasheet for Chicken TCRyd Antibody : Biotin (OASB02396) |
---|
Tested Species Reactivity | Chicken |
---|---|
Predicted Species Reactivity | Chicken |
Product Format | Liquid. Phosphate buffered saline containing 0.1% sodium azide |
Clonality | Monoclonal |
Host | Mouse |
Conjugation | Biotin |
Application | FC, IHC-F, IHC-P, IP |
Additional Information | Description: The monoclonal antibody TCR-1 precipitates a heterodimer of Mr 90 kDa (two bands of Mr 50 kDa and 40 kDa upon reduction) on chicken peripheral blood T cells. Deglycosylation of the heterodimer yields two polypeptides of Mr 35 kDa and 32 kDa. Unlike human and mouse in which gamma/delta cells comprise a minor subset of T lymphocytes in the circulation, the chicken has a relatively large subset of gamma/delta T cells. The frequency of TCR gamma/delta cells is typically 20-25% of the total blood T cells but may reach approximately 50% in chickens of six- months of age. The majority of TCR gamma/delta+ cells in the thymus and blood are CD4-CD8- although a small subset of them may express CD8 or CD4 coreceptors. However, when the TCR gamma/delta+ cells migrate into the spleen and intestine most of them begin to express CD8. Although the biological function of gamma/delta T cells is unclear, they are clearly capable of cytotoxic activity in vitro. The CD8+ gamma/deta T cells may also be involved in down-regulation of the immune response. They cannot, however, induce a graft-vs-host (GVH) reactions. |
Reconstitution and Storage | Store at 2-8C |
Immunogen | Outbred chicken thymocytes and Ig-negative blood lymphocytes |
Concentration | 0.5 mg/mL |
Specificity | TCRgd |
-
What is the species homology for "Chicken TCRyd Antibody : Biotin (OASB02396)"?
The tested species reactivity for this item is "Chicken". This antibody is predicted to have homology to "Chicken".
-
How long will it take to receive "Chicken TCRyd Antibody : Biotin (OASB02396)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
-
What buffer format is "Chicken TCRyd Antibody : Biotin (OASB02396)" provided in?
This item is provided in "Liquid. Phosphate buffered saline containing 0.1% sodium azide".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Chicken TCRyd Antibody : Biotin (OASB02396)"?
This target may also be called "" in publications.
-
What is the shipping cost for "Chicken TCRyd Antibody : Biotin (OASB02396)"?
The shipping cost for this item is within the US. Please contact us for specific shipping for international orders.
-
What is the guarantee for "Chicken TCRyd Antibody : Biotin (OASB02396)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
-
Can I get bulk pricing for "Chicken TCRyd Antibody : Biotin (OASB02396)"?
You can get bulk pricing for this item by going here.
-
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Chicken TCRyd Antibody : Biotin (OASB02396)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
-
What are positive controls for ""?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What are negative controls for ""?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What other proteins interact with ""?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
-
What biological processes are associated with ""?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
-
What cellular components are associated with ""?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
-
What protein functions are associated with ""?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.