Cholic acid-13C [52886-36-9]
Referentie HY-N0324S2-10mg
Formaat : 10mg
Merk : MedChemExpress
Cholic acid-13C is the 13C-labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.
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Cholic acid-13C Chemical Structure
CAS No. : 52886-36-9
This product is a controlled substance and not for sale in your territory.
Based on 1 publication(s) in Google Scholar
Other Forms of Cholic acid-13C:
- Cholic acid In-stock
Description |
Cholic acid-13C is the 13C-labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. |
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In Vitro |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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Masse moléculaire |
409.56 |
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Formule |
C2313CH40O5 |
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CAS No. |
52886-36-9 |
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Unlabeled CAS |
81-25-4 |
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Appearance |
Solid |
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Color |
White to off-white |
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SMILES |
O[C@H]1[C@@]2(02)[C@@]3(02)[C@@]([C@@](CC3)(02)[C@H](C)CC[13C](O)=O)([C@H](C[C@]2(02)[C@@]4([C@](C[C@@H](CC4)O)(02)C1)C)O)C |
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Livraison | Room temperature in continental US; may vary elsewhere. |
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Stockage |
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Solvant et solubilité |
In Vitro:
DMSO : ≥ 100 mg/mL (244.16 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) *"≥" means soluble, but saturation unknown. Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
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Pureté et documentation |
Purity: ≥98.0% |
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Références |
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Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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DMSO | 1 mM | 2.4416 mL | 12.2082 mL | 24.4164 mL | 61.0411 mL |
5 mM | 0.4883 mL | 2.4416 mL | 4.8833 mL | 12.2082 mL | |
10 mM | 0.2442 mL | 1.2208 mL | 2.4416 mL | 6.1041 mL | |
15 mM | 0.1628 mL | 0.8139 mL | 1.6278 mL | 4.0694 mL | |
20 mM | 0.1221 mL | 0.6104 mL | 1.2208 mL | 3.0521 mL | |
25 mM | 0.0977 mL | 0.4883 mL | 0.9767 mL | 2.4416 mL | |
30 mM | 0.0814 mL | 0.4069 mL | 0.8139 mL | 2.0347 mL | |
40 mM | 0.0610 mL | 0.3052 mL | 0.6104 mL | 1.5260 mL | |
50 mM | 0.0488 mL | 0.2442 mL | 0.4883 mL | 1.2208 mL | |
60 mM | 0.0407 mL | 0.2035 mL | 0.4069 mL | 1.0174 mL | |
80 mM | 0.0305 mL | 0.1526 mL | 0.3052 mL | 0.7630 mL | |
100 mM | 0.0244 mL | 0.1221 mL | 0.2442 mL | 0.6104 mL |
Cholic acid-13C Related Classifications
- Metabolic Disease
- Metabolic Enzyme/Protease
- Endogenous Metabolite
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Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.
Keywords:
Cholic acid-13C52886-36-9Endogenous MetaboliteInhibitorinhibitorinhibit