CLK4 antibody - N-terminal region

Referentie ARP30645_P050

Formaat : 100ul

Merk : Aviva Systems Biology

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Datasheets/ManualsPrintable datasheet for anti-CLK4 (ARP30645_P050) antibody
Product Info
Publications

Eisenreich, A. et al. Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells. Oncol. Rep. 30, 462-70 (2013). 23604472

Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human CLK4
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 93%; Yeast: 91%
Peptide SequenceSynthetic peptide located within the following region: RSRRSSPKRKRNRHCSSHQSRSKSHRRKRSRSIEDDEEGHLICQSGDVLR
Concentration0.5 mg/ml
Blocking PeptideFor anti-CLK4 (ARP30645_P050) antibody is Catalog # AAP30645 (Previous Catalog # AAPP01302)
Gene SymbolCLK4
Gene Full NameCDC-like kinase 4
Alias SymbolsDKFZp686A20267
NCBI Gene Id57396
Protein NameDual specificity protein kinase CLK4
Description of TargetThe protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined.
Uniprot IDQ9HAZ1
Protein Accession #NP_065717
Nucleotide Accession #NM_020666
Protein Size (# AA)481
Molecular Weight57
Protein InteractionsKPNA1; KRTAP10-3; KRTAP10-8; KRTAP10-9; KRTAP10-7; CLK4; SRRM2; AHCYL2; SUB1; RASA4; SRPK1; RNF181; CLASRP; UBL5; HSPB2;
  1. What is the species homology for "CLK4 Antibody - N-terminal region (ARP30645_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast".

  2. How long will it take to receive "CLK4 Antibody - N-terminal region (ARP30645_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "CLK4 Antibody - N-terminal region (ARP30645_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CLK4 Antibody - N-terminal region (ARP30645_P050)"?

    This target may also be called "DKFZp686A20267" in publications.

  5. What is the shipping cost for "CLK4 Antibody - N-terminal region (ARP30645_P050)"?

    The shipping cost for this item is within the US. Please contact us for specific shipping for international orders.

  6. What is the guarantee for "CLK4 Antibody - N-terminal region (ARP30645_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CLK4 Antibody - N-terminal region (ARP30645_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "57".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CLK4 Antibody - N-terminal region (ARP30645_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CLK4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CLK4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CLK4"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CLK4"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CLK4"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CLK4"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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