Dcr-1, ID (Endoribonuclease dcr-1, dcr-1, K12H4.8)

Referentie D1499-08A-200ul

Formaat : 200ul

Merk : US Biological

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D1499-08A Dcr-1, ID (Endoribonuclease dcr-1, dcr-1, K12H4.8)

Clone Type
Polyclonal
Host
rabbit
Source
c.elegans
Swiss Prot
P34529
Isotype
IgG
Grade
Purified
Applications
E
Crossreactivity
Ce
Accession #
NP_498761
Shipping Temp
Blue Ice
Storage Temp
-20°C

The Dcr-1 gene encodes a bidentate ribonuclease that is homologous to E. coli RNAse III. Dcr-1 is required both for RNA interference and for synthesis of small developmental RNAs. Dcr-1 interacts in vivo with RDE-4, a double-stranded RNA (dsRNA) binding protein required for RNAi that interacts with trigger dsRNAs and may function to deliver dsRNAs to Dcr-1 for endonucleolytic processing.||Applications: |Suitable for use in ELISA. Other applications not tested.||Recommended Dilution:|Optimal dilutions to be determined by the researcher.||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Applications
Product Type: Pab|Isotype: IgG|Host: rabbit|Source: c.elegans|Concentration: Not Determined |Form: Supplied as a liquid in PBS, 0.09% sodium azide.|Purity: Purified by ammonium sulfate precipitation.|Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1068-1097 of C. elegans Dcr-1.|Specificity: Recognizes C. elegans Dcr-1.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1068-1097 of C. elegans Dcr-1.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity
Purified by ammonium sulfate precipitation.
Specificity
Recognizes C. elegans Dcr-1.
References
1.Duchaine TF, et al. 2006. Cell 124:343-354. 2.Denli AM, et al. 2004. Nature 432:231-235. 3.Tabara H, et al. 2002. Cell 109:861-871. 4.Grishok A, et al. 2001. Cell 106:23-34. 5.Knight SW, et al. 2001. Science 293:2269-2271.