EGFR (pY869) Antibody is a Rabbit Polyclonal antibody against EGFR (pY869). The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
Research Articles on EGFR (pY869)
| Target | EGFR (pY869) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic phosphorylated peptide around Y845 of human EGFR. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P00533 (UniProt, ExPASy) |
| UniProt Entry Name | EGFR_HUMAN |
| Gene Symbol | EGFR |
| GeneID | 1956 |
| NCBI Accession | NP_005219.2 |
| KEGG | hsa:1956 |
| String | 9606.ENSP00000275493 |
| Molecular Weight | Calculated MW: 134 kDa Observed MW: 200 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |