FAU Polyclonal Antibody, Biotin Conjugated
Referentie bs-13148R-Biotin
Formaat : 100ul
Merk : Bioss
FAU Polyclonal Antibody, Biotin Conjugated
Applications
Predicted Reactivity
Overview | |
Catalog # | bs-13148R-Biotin |
Product Name | FAU Polyclonal Antibody, Biotin Conjugated |
Applications | WB, ELISA, IHC-P, IHC-F |
Predicted Reactivity | Human, Mouse, Rat, Cow, Sheep, Pig, Horse |
Specifications | |
Conjugation | Biotin |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human FAU |
Immunogen Range | 11-74/74 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C for 12 months. |
Target | |
Gene ID | 2197 |
Swiss Prot | P62861 |
Subcellular location | Cytoplasm, Nucleus |
Synonyms | 40S ribosomal protein S30; asr1; FAU; FAU encoded ubiquitin like protein; FAU1; FBR MuSV associated ubiquitously expressed; Finkel Biskis Reilly murine sarcoma virus FBR MuSV ubiquitously expressed fox derived; Finkel Biskis Reilly murine sarcoma virus FBR MuSV ubiquitously expressed; Finkel Biskis Reilly murine sarcoma virus ubiquitously expressed; FLJ22986; Fub1; Fubi; MNSFbeta; Monoclonal nonspecic suppressor factor beta; Ribosomal protein S30; RPS30; S30; UBIM_HUMAN; Ubiquitin like protein fubi and ribosomal protein S30; Ubiquitin like protein fubi; Ubiquitin like S30 fusion protein; Ubiquitin-like protein FUBI. |
Background | The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. A wide range of enzymes facilitate in the proteolytic Ub pathway, including monoclonal nonspecific suppressor factor-beta (MNSF-beta), a subunit of MNSF, which is a lymphokine product of a murine T cell hybrid-oma that restricts the production of LPS-induced immunoglobulin secreting cells in an antigen-nonspecific manner. MNSF-beta is a ubiquitin-like fusion protein consisting of the ribosomal protein S30 and a protein that shares 36% sequence identity with ubiquitin. This ubiquitin-like segment (Ubi-L) can be cleaved from MNSF-beta in the cytosol. |
Application Dilution | |
WB | 1:300-5000 |
ELISA | 1:500-1000 |
IHC-P | 1:200-400 |
IHC-F | 1:100-500 |