Glycolithocholic Acid (Sodium Salt)

Glycolithocholic Acid (Sodium Salt)
Catalog number: B2012724
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: N/A
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: glycine-conjugated form of lithocholic acid
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Tserng KY, Klein PD. Synthesis of sulfate esters of lithocholic acid, glycolithocholic acid, and taurolithocholic acid with sulfur trioxide-triethylamine J Lipid Res. 1977 Jul;18(4):491-5.
2: Grzych G, Chávez-Talavera O, Descat A, Thuillier D, Verrijken A, Kouach M, Legry V, Verkindt H, Raverdy V, Legendre B, Caiazzo R, Van Gaal L, Goossens JF, Paumelle R, Francque S, Pattou F, Haas JT, Tailleux A, Staels B. NASH-related increases in plasma bile acid levels depend on insulin resistance JHEP Rep. 2020 Dec 16;3(2):100222.
3: Kuipers F, Derksen JP, Gerding A, Scherphof GL, Vonk RJ. Biliary lipid secretion in the rat. The uncoupling of biliary cholesterol and phospholipid secretion from bile acid secretion by sulfated glycolithocholic acid Biochim Biophys Acta. 1987 Nov 21;922(2):136-44.
4: Bansal S, Lau AJ. Inhibition of Human Sulfotransferase 2A1-Catalyzed Sulfonation of Lithocholic Acid, Glycolithocholic Acid, and Taurolithocholic Acid by Selective Estrogen Receptor Modulators and Various Analogs and Metabolites J Pharmacol Exp Ther. 2019 Jun;369(3):389-405.
5: Jia Y, Yang X, Wilson LM, Mueller NT, Sears CL, Treisman GJ, Robinson KA. Diet-Related and Gut-Derived Metabolites and Health Outcomes: A Scoping Review Metabolites. 2022 Dec 14;12(12):1261.
6: Kuipers F, Havinga R, Vonk RJ. Cholestasis induced by sulphated glycolithocholic acid in the rat: protection by endogenous bile acids Clin Sci (Lond). 1985 Feb;68(2):127-34.
7: Kuipers F, Hardonk MJ, Vonk RJ, van der Meer R. Bile secretion of sulfated glycolithocholic acid is required for its cholestatic action in rats Am J Physiol. 1992 Feb;262(2 Pt 1):G267-73.
8: Mantovani A, Dalbeni A, Peserico D, Cattazzo F, Bevilacqua M, Salvagno GL, Lippi G, Targher G, Danese E, Fava C. Plasma Bile Acid Profile in Patients with and without Type 2 Diabetes Metabolites. 2021 Jul 14;11(7):453.
9: Ginos BNR, Navarro SL, Schwarz Y, Gu H, Wang D, Randolph TW, Shojaie A, Hullar MAJ, Lampe PD, Kratz M, Neuhouser ML, Raftery D, Lampe JW. Circulating bile acids in healthy adults respond differently to a dietary pattern characterized by whole grains, legumes and fruits and vegetables compared to a diet high in refined grains and added sugars: A randomized, controlled, crossover feeding study Metabolism. 2018 Jun;83:197-204.
10: Tian M, Yan J, Zhang H, Wei Y, Zhang M, Rao Z, Zhang M, Wang H, Wang Y, Li X. Screening and validation of biomarkers for cadmium-induced liver injury based on targeted bile acid metabolomics Environ Pollut. 2022 May 1;300:118837.

Products Related to Glycolithocholic Acid (Sodium Salt) can be found at Chemicals