Reagentia en instrumenten voor immunologie, celbiologie en moleculaire biologie.
 
> Goat anti-EWS / EWSR1, Biotinylated Antibody

Goat anti-EWS / EWSR1, Biotinylated Antibody

Afdrukken Afdrukken
Log in alstublieft

Referentie AF4479a

Formaat : 100ug

Merk : Abcepta

Meer informatie aanvragen

Neem contact op met een lokale distributeur :


Telefoonnummer : +1 850 650 7790

 
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, Pep-ELISA
Primary Accession Q01844
Other Accession NP_053733.2, NP_005234.1, NP_001156757.1, NP_001156758.1, NP_001156759.1
Reactivity Human, Mouse, Rat, Pig, Bovine
Host Goat
Clonality Polyclonal
Clone Names EWSR1
Calculated MW 68478 Da
Additional Information
Gene ID 2130
Other Names EWSR1; EWS; Ewing sarcoma breakpoint region 1; EWS/FLI fusion protein; EWSR1/ZNF384 fusion protein; Ewings sarcoma EWS-Fli1 (type 1) oncogene; bK984G1.4 (Ewing sarcoma breakpoint region 1 protein); extraskeletal myxoid chondrosarcoma EWS/TEC/CHN fusion pr
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Immunogen This antibody is expected to recognize all five reported isoforms (NP_053733.2; NP_005234.1; NP_001156757.1; NP_001156758.1; NP_001156759.1).
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat anti-EWS / EWSR1, Biotinylated Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EWSR1
Synonyms EWS
Function Might normally function as a transcriptional repressor. EWS- fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.
Cellular Location Nucleus. Cytoplasm. Cell membrane. Note=Relocates from cytoplasm to ribosomes upon PTK2B/FAK2 activation
Tissue Location Ubiquitous.