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> GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) Antibody - With BSA and Azide

GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) Antibody - With BSA and Azide

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Referentie AH12453-U0020

Formaat : 20ug

Merk : Abcepta

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  • IHC - GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) Antibody - With BSA and Azide AH12453-20
    Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with GRP94 Monoclonal Antibody (9G10.F8.2).
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, FC
Primary Accession P14625
Other Accession 7184, 192374
Reactivity Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Chicken, Bovine, Sheep, Xenopus, Horse, Guinea Pig, Dog
Host Rat
Clonality Monoclonal
Isotype Rat / IgG2a, kappa
Clone Names 9G10.F8.2
Calculated MW 94kDa
Additional Information
Gene ID 7184
Other Names Endoplasmin, 94 kDa glucose-regulated protein, GRP-94, Heat shock protein 90 kDa beta member 1, Tumor rejection antigen 1, gp96 homolog, HSP90B1, GRP94, TRA1
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HSP90B1 (HGNC:12028)
Function Molecular chaperone that functions in the processing and transport of secreted proteins (By similarity). When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD) (PubMed:18264092). Has ATPase activity (By similarity). May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum- Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10 (PubMed:32272059).
Cellular Location Endoplasmic reticulum lumen. Sarcoplasmic reticulum lumen {ECO:0000250|UniProtKB:P41148}. Melanosome Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.