Human Acyl coenzyme A Thioesterase 4 (ACOT4) activation kit by CRISPRa

Referentie GA114795

Formaat : 1kit

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Human Acyl coenzyme A Thioesterase 4 (ACOT4) activation kit by CRISPRa

Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ACOT4
Locus ID 122970
Components

GA114795G1, Acyl coenzyme A Thioesterase 4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114795G2, Acyl coenzyme A Thioesterase 4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114795G3, Acyl coenzyme A Thioesterase 4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_152331
UniProt ID Q8N9L9
Synonyms PTE-Ib; PTE1B; PTE2B
Summary Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (PubMed:16940157). ACOT4 is a peroxisomal succinyl-coenzyme A thioesterase can also hydrolyze glutaryl-CoA and long chain saturated acyl-CoAs (PubMed:16940157).[UniProtKB/Swiss-Prot Function]
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SKU Description Size
KN410550 ACOT4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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