Human Lysosomal acid lipase (LIPA) activation kit by CRISPRa

Referentie GA102702

Formaat : 1kit

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Human Lysosomal acid lipase (LIPA) activation kit by CRISPRa

SKU
GA102702
LIPA CRISPRa kit - CRISPR gene activation of human lipase A, lysosomal acid type
2 Weeks*
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol LIPA
Locus ID 3988
Components

GA102702G1, Lysosomal acid lipase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102702G2, Lysosomal acid lipase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102702G3, Lysosomal acid lipase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000235, NM_001127605, NM_001288979, NR_110233
UniProt ID P38571
Synonyms CESD; LAL
Summary This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2014]
SKU Description Size
KN401637 LIPA - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit

Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.