Human Phospholipase C beta 2 (PLCB2) activation kit by CRISPRa

Referentie GA103590

Formaat : 1kit

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Human Phospholipase C beta 2 (PLCB2) activation kit by CRISPRa

Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PLCB2
Locus ID 5330
Components

GA103590G1, Phospholipase C beta 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103590G2, Phospholipase C beta 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103590G3, Phospholipase C beta 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001284297, NM_001284298, NM_001284299, NM_004573
UniProt ID Q00722
Synonyms PLC-beta-2
Summary The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses. [provided by RefSeq, Jan 2017]
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SKU Description Size
KN419009 PLCB2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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