Human TNF alpha ELISpot Pair, 10 x 96-well

CAT#: EA101815

Human TNF alpha ELISpot Pair, 10 x 96-well


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Specifications

Product Data
Format 10 x 96-well
Assay Type Enzyme-Linked ImmunoSpot (ELISpot)
Signal Colorimetric
Specificity Recognizes natural human TNF-a
Cross Reactivity No cross reactivity with other human cytokines. Cross reactivity with macac TNF-a. No interference with soluble TNFR I and TNFR II.
Components ELISpot matched antibody pairs are extensively validated and include pre-titrated capture antibody and biotinylated detection antibody. Antibodies are supplied in quantities sufficient for 10 x 96 samples.
Background This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]
Gene Symbol TNF
Gene ID 7124

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