INDY
Referentie orb1473181-100mg
Formaat : 100mg
Merk : Biorbyt
INDY
Catalog Number: orb1473181
Catalog Number | orb1473181 |
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Category | Small Molecules |
Description | INDY is a potent and ATP-competitive Dyrk1A and Dyrk1B inhibitor with IC50s of 0.24 μM and 0.23 μM, respectively. INDY binds in the ATP pocket of the enzyme and has a Ki value of 0.18 μM for Dyrk1A. INDY sharply reduces the self-renewal capacity of normal and tumorigenic cells in primary Glioblastoma (GBM) cell lines and neural progenitor cells. |
CAS Number | [1169755-45-6] |
MW | 235.3 |
SMILES | CC(/C=C1SC2=CC=C(O)C=C2N\1CC)=O |
Formula | C12H13NO2S |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |