Interleukin 17, Recombinant, Mouse

Referentie 149694-25ug

Formaat : 25ug

Merk : US Biological

Meer informatie aanvragen

Neem contact op met een lokale distributeur :


Telefoonnummer : +1 850 650 7790


149694 Interleukin 17, Recombinant, Mouse (IL-17, IL17, Interleukin-17A, IL-17A, Cytotoxic T-lymphocyte-associated Antigen 8, CTLA-8, Il17a, Ctla8, Il17)

Clone Type
Polyclonal
Swiss Prot
Q62386
Grade
Highly Purified
Shipping Temp
Blue Ice
Storage Temp
-20°C

The originally described IL-17 protein, now known as IL-17A, is a disulfide linked homodimer, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells. Recombinant mouse IL-17A is a 30kD disulfide-linked homodimer of two 133aa polypeptide chains.||Source:|Recombinant protein corresponding to mouse IL-17A, expressed in E.coli.||Biological Activity:|Measured by its ability to induce IL-6 production by NIH 3T3 cells.||Storage and Stability:|Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Applications
Source: Recombinant, E. coli|Purity: ≥98% (SDS-PAGE and HPLC). Endotoxin: ≤0.1ng/ug (1EU/ug).|Form: Supplied as a lyophilized powder. Reconstitute with sterile dH2O to ≥0.1mg/ml.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Form
Supplied as a lyophilized powder. Reconstitute with sterile dH2O to ≥0.1mg/ml.
Purity
≥98% (SDS-PAGE and HPLC). Endotoxin: ≤0.1ng/ug (1EU/ug).