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> Mannose Receptor antibody [15-2] (PerCP-Cy5.5)

Mannose Receptor antibody [15-2] (PerCP-Cy5.5)

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Referentie GTX00491-11-100test

Formaat : 100test

Merk : Genetex

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Telefoonnummer : +1 850 650 7790

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 15-2

Isotype

 IgG1

Application

 ICC/IF, IHC-P, FACS

Reactivity

 Human, Mouse, Rat
Package
100 test
Datasheet File
View product citations for antibody GTX00491-11 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-P Assay dependent
FACS 4 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified human mannose receptor

Purification

Purified by size-exclusion chromatography

Conjugation

Peridinin-chlorophyll proteins-Cyanine5.5 (PerCP-Cy5.5)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.

TARGET

Synonyms

CD206 , CLEC13D , CLEC13DL , MMR , MRC1 , MRC1L1 , bA541I19.1 , hMR , mannose receptor, C type 1 , Mannose Receptor , mrc1 , mannose receptor C-type 1

Cellular Localization

Endosome membrane,Cell membrane

Background

The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]

Database

Clone Reference

GH Han et al. Cell Prolif 2021; 54:e13050 Transplantation of tauroursodeoxycholic acid-inducing M2-phenotype macrophages promotes an anti-neuroinflammatory effect and functional recovery after spinal cord injury in rats
Application : ICC/IF, IHC-P, FACS
Reactivity : Rat
GK Katara et al. Oncogene 2014; 33 (49):5649-54 Tumor-associated vacuolar ATPase subunit promotes tumorigenic characteristics in macrophages
Application : ICC/IF
Reactivity : Human
PA Walker et al. J Neuroinflammation 2012; 9:228 Intravenous multipotent adult progenitor cell therapy after traumatic brain injury: modulation of the resident microglia population
Application : ICC/IF
Reactivity : Mouse

REVIEW

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Clone Reference
GH Han et al. Cell Prolif 2021; 54:e13050 Transplantation of tauroursodeoxycholic acid-inducing M2-phenotype macrophages promotes an anti-neuroinflammatory effect and functional recovery after spinal cord injury in rats
Application : ICC/IF, IHC-P, FACS
Reactivity : Rat
GK Katara et al. Oncogene 2014; 33 (49):5649-54 Tumor-associated vacuolar ATPase subunit promotes tumorigenic characteristics in macrophages
Application : ICC/IF
Reactivity : Human
PA Walker et al. J Neuroinflammation 2012; 9:228 Intravenous multipotent adult progenitor cell therapy after traumatic brain injury: modulation of the resident microglia population
Application : ICC/IF
Reactivity : Mouse
SDS
PBS.pdf
Sodium Azide.pdf