Application ![]()
| WB, E |
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Primary Accession | Q8NEM0 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 95 KDa |
Gene ID | 79648 |
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Other Names | Microcephalin, MCPH1 |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | MCPH1 (HGNC:6954) |
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Function | Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex. |
Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome |
Tissue Location | Expressed in fetal brain, liver and kidney. |

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Background
Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex.
References
Barry C.,et al.Patent number WO0114550, 01-MAR-2001.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Nusbaum C.,et al.Nature 439:331-335(2006).
Lin S.-Y.,et al.Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
Jackson A.P.,et al.Am. J. Hum. Genet. 71:136-142(2002).