Conjugation | FITC |
---|---|
Antigen | CD20 |
Clone | 2H7 |
Isotype | IgG2b, k |
Applications | FC |
Reactivity | Baboon, Cynomolgus monkey, Human, Rhesus |
Host | Mouse |
Clonality | Monoclonal |
Primary/Secondary | Primary |
Storage | 2-8°C |
Status | RUO |
Excitation Laser | Blue (488nm) |
CD20 FITC
Catalog #
Size
Description:
Antibody clone 2H7 recognizes the large extracellular loop of human CD20, mapped to the peptide sequence YNCEPANPSEKNSPST. CD20, a 33-36 kDa non-glycosylated type 1 transmembrane protein, is expressed by developing, resting and mature B cells, some follicular dendritic cells, and a small subset of mature T cells. B cell CD20 expression is lost upon differentiation into plasma cells. Functionally, CD20 activation contributes to B cell activation, proliferation, and differentiation.
Antibody clone 2H7 recognizes the large extracellular loop of human CD20, mapped to the peptide sequence YNCEPANPSEKNSPST. CD20, a 33-36 kDa non-glycosylated type 1 transmembrane protein, is expressed by developing, resting and mature B cells, some follicular dendritic cells, and a small subset of mature T cells. B cell CD20 expression is lost upon differentiation into plasma cells. Functionally, CD20 activation contributes to B cell activation, proliferation, and differentiation.