Mouse Anti-Human CD71-PE

Referentie 9670-09

Formaat : 100tests

Merk : Southern Biotech

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More Information
Clone RVS-10
Isotype Mouse IgG1κ
Isotype Control Mouse IgG1-PE (15H6)
Specificity Human CD71
Alternative Names TFR, TRFR, transferrin receptor, T9
Description CD71 is a 95 kDa type II heterodimeric transmembrane glycoprotein that is the receptor for transferrin. CD71 expression is very low on resting leukocytes but is upregulated upon activation. CD71 plays a critical role in cell proliferation by controlling the supply of iron which is essential for many metabolic pathways through the binding and endocytosis of transferrin.
Conjugate PE (R-phycoerythrin)
Buffer Formulation Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer
Clonality Monoclonal
Concentration Lot specific
Volume 1.0 mL
Recommended Storage 2-8°C; Avoid exposure to light; Do not freeze
Applications Flow Cytometry – Quality tested 5
Immunocytochemistry – Reported in literature 1-3
Drug Delivery – Reported in literature 4

RRID Number AB_2797063
Gene ID 7037 (Human)
Gene ID Symbol TFRC (Human)
Gene ID Aliases CD71; IMD46; T9; TFR; TFR1; TR; TRFR; p90
UniProt ID P02786 (Human
UniProt Name TFR1_HUMAN (Human)
Documentation
Technical Bulletin Safety Datasheet

Certificate of Analysis Lookup

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  1. 1. O'Donnell V, LaRocco M, Duque H, Baxt B. Analysis of foot-and-mouth disease virus internalization events in cultured cells. J Virol. 2005;79:8506-18. (ICC)
  2. 2. Keyel PA, Mishra SK, Roth R, Heuser JE, Watkins SC, Traub LM. A single common portal for clathrin-mediated endocytosis of distinct cargo governed by cargo-selective adaptors. Mol Biol Cell. 2006;17:4300-17. (ICC)
  3. 3. Di Pucchio T, Chatterjee B, Smed-Sörensen A, Clayton S, Palazzo A, Montes M, et al. Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I. Nat Immunol. 2008;9:551-7. (ICC)
  4. 4. Patil R, Portilla-Arias J, Ding H, Inoue S, Konda B, Hu J. Temozolomide delivery to tumor cells by a multifunctional nano vehicle based on poly(β-L-malic acid). Pharm Res. 2010;27:2317-29. (Drug Delivery)
  5. 5. Seiffert M, Cant C, Chen Z, Rappold I, Brugger W, Kanz L, et al. Human signal-regulatory protein is expressed on normal, but not on subsets of leukemic myeloid cells and mediates cellular adhesion involving its counterreceptor CD47. Blood. 1999;94:3633-43. (FC)

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