Mouse Mgst2 activation kit by CRISPRa
Referentie GA213046
Formaat : 1kit
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Mouse Mgst2 activation kit by CRISPRa
SKU
GA213046
Mgst2 CRISPRa kit - CRISPR gene activation of mouse microsomal glutathione S-transferase 2
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | Mgst2 |
| Locus ID | 211666 |
| Components | GA213046G1, Mgst2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213046G2, Mgst2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213046G3, Mgst2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001310482, NM_174995 |
| UniProt ID | A2RST1 |
| Synonyms | GST2; MGST-II |
| Summary | Catalyzes several different glutathione-dependent reactions. Catalyzes the glutathione-dependent reduction of lipid hydroperoxides, such as 5-HPETE. Has glutathione transferase activity, toward xenobiotic electrophiles, such as 1-chloro-2, 4-dinitrobenzene (CDNB). Catalyzes also the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4 (LTC4) (By similarity). Involved in oxidative DNA damage induced by ER stress and anticancer agents by activating LTC4 biosynthetic machinery in nonimmune cells (PubMed:26656251).[UniProtKB/Swiss-Prot Function] |
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| FAQs |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN510072 | Mgst2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.