Mouse Monoclonal Anti-EGFR (Epidermal Growth Factor Receptor) (Clone GFR450)
Referentie 24-1956-MSM1-500ul
Formaat : 500ul
Merk : American Research Products
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Anti-EGFR (Epidermal Growth Factor Receptor), Monoclonal Antibody
| Product Name | Anti-EGFR (Epidermal Growth Factor Receptor), Monoclonal Antibody |
|---|---|
| Description | This monoclonal antibody recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas. |
| Synonyms | Erbb1, ERBB1, Errp, HER1, mENA, PIG61, Proto-oncogene c-ErbB-1, Receptor Tyrosine Protein Kinase, ErbB1, Urogastrone, wa2, Wa5 |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | GFR450 |
| Immunogen | Recombinant extracellular domain of human EGFR protein |
| Isotype | IgG2a, kappa |
| Reactivity | Human |
| Applications | FC, IF, IHC |
| Form | 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1mg/ml. |
| Gene Id | 1956 |
| Uniprot | P00533 |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| References | Tungekar MF et. al. Journal of Clinical Pathology. 51: 583-587 (1998). |
| Supplier | ARP |
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