pan Cytokeratin (4+5+6+8+10+13+18) Mouse Monoclonal Antibody [Clone ID: C-11]

Specifications

Product Data
Clone Name	C-11
Applications	FC, IF, IHC, IP, WB
Recommended Dilution	Western Blot. Flow Cytometry: 0.5 µg/ml. Immunoprecipitation. Immunocytochemistry. Immunohistochemistry on Paraffin Sections.
Reactivities	Mammalian, Amphibian
Host	Mouse
Isotype	IgG1
Clonality	Monoclonal
Immunogen	Keratin-enriched preparation from human epidermoid carcinoma cell line A431
Specificity	The antibody reacts with Cytokeratin peptides 4, 5, 6, 8, 10, 13, 18 (recognized epitope conserved within all species). Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.
Formulation	PBS, pH~7.4 State: Purified State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE) Preservative: 15 mM Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage	Store undiluted at 2-8°C. DO NOT FREEZE!
Stability	Shelf life: one year from despatch.
Background	Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.
Synonyms	pan Keratin, Cytokeratin pan-reactive
Reference Data