Placental lactogen (CSH1) (NM_001317) Human 3' UTR Clone

Specifications

Product Data
Vector	pMirTarget
Species	Human
Transfection Reporter	RFP
Assay Reporter	Luciferase
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Symbol	CSH1
Synonyms	CS-1; CSA; CSMT; GHB3; hCS-1; hCS-A; PL
ACCN	NM_001317
Insert Size	134 bp
Sequence Data	Insert Sequence (showhide) >SC200758 3’UTR clone of NM_001317 The sequence shown below is from the reference sequence of NM_001317. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CGCTCTGTGGAGGGCAGCTGTGGCTTCTAGGTGCCCGAGTAGCATCCTGTGACCCCTCCCCAGTGCCTC TCCTGGCCCTGAAGGTGCCACTCCAGTGCCCACCAGCCTTGTCCTAATAAAATTAAGTTGTATCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Product Components	The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.
Reference Data
RefSeq	NM_001317.6
Summary	The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq, Jul 2008]
Locus ID	1442
MW	4.9