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> Prazosin hydrochloride

Prazosin hydrochloride

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Referentie M5895-500mg

Formaat : 500mg

Merk : AbMole Bioscience

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Telefoonnummer : +1 850 650 7790

All AbMole products are for research use only, cannot be used for human consumption.

Prazosin hydrochloride Structure
Synonym:

cp-12299-1

Quality Control & Documentation
Biological Activity

Prazosin hydrochloride, a Quinazoline derivative, is a well-tolerated, CNS-active α1-adrenergic receptor antagonist for the research of high blood pressure and alcohol use disorders. Prazosin hydrochloride potently inhibits Norepinephrine (NE)-stimulated 45Ca efflux with an IC50 of 0.15 nM. Prazosin hydrochloride inhibits organic cation transporters OCT-1 and OCT-3 with IC50s of 1.8, and 13 μM, respectively.

Chemical Information
Molecular Weight 419.86
Formula C19H21N5O4·HCl
CAS Number 19237-84-4
Solubility (25°C) DMSO 7 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Haagsman AN, et al. Vet Rec. Comparison of terazosin and prazosin for treatment of vesico-urethral reflex dyssynergia in dogs.